Postdoctoral Fellow
University of California San Francisco
Annamarie E. Bustion, PhD is a CERSI UCSF/Genentech Postdoctoral Fellow in Clinical Pharmacology with interdisciplinary expertise spanning pharmacometrics, chemoinformatics, bioinformatics, and machine learning.
Currently, in the Clinical Pharmacology Modeling & Simulation group at Genentech, she integrates pharmacometrics, machine learning, and real-world data to support drug development. Her work focuses on population PK/PD modeling and simulation, multivariable survival models, and the co-development of a Drug-Drug Interaction Dashboard that leverages real-world claims data.
Prior to Genentech, Annamarie completed postdoctoral research in the Savic Lab at UCSF, where she applied chemoinformatics-informed machine learning to predict drug partitioning into TB lung lesions, modeled the spatiotemporal kinetics of diarylquinolines to understand resistance emergence, and linked preclinical site-of-action exposures to clinical trial outcomes.
She earned her PhD in Pharmaceutical Sciences and Pharmacogenomics from UCSF, where she developed SIMMER, a computational tool that predicts bacterial enzymes responsible for drug metabolism in the human gut microbiome.
Annamarie’s work has been recognized with multiple fellowships and awards, including the PhRMA Foundation Predoctoral Informatics Fellowship and the UCSF Apple Teaching Award. She is deeply committed to mentorship and education, guiding scientists at all levels—from postdocs and graduate students to undergraduate researchers and even elementary school classrooms.